Prescription · statins
Statins
Atorvastatin · Rosuvastatin · Simvastatin · Pravastatin
Mechanism
Inhibit HMG-CoA reductase, reducing cholesterol synthesis in the liver.
Environmental footprint
Liver enzyme monitoring sometimes needed. Muscle symptoms in susceptible individuals. Real cardiovascular benefit for indicated populations.
What the evidence shows
Strong cardiovascular outcome evidence in primary and secondary prevention. Muscle pain (myopathy) in 5–10% of users. CoQ10 depletion proposed as mechanism for muscle symptoms.
Biome maps medication footprints; it does not recommend starting, stopping, or changing any prescription. Always consult your prescriber or pharmacist.